Search results for "Sicilian population"
showing 7 items of 7 documents
Isozyme analysis of genetic diversity in wild Sicilian populations of Brassica sect. Brassica in view of genetic resources management
2004
In Sicily and in the small surrounding islands the section Brassica of the genus Brassica comprises five species, B. insularis Moris, B. incana Ten., B. macrocarpa Guss., B. rupestris Raf. and B. villosa Biv. These taxa represent a genetic resource as relatives of kale crops but some populations are endangered or threatened, thus isozyme analyses were performed to assess the genetic diversity degree at population and species levels in order to assist the design of conservation management programs. Eleven loci from five enzyme systems (aconitase, leucine aminopeptidase, 6-phosphogluconate dehydrogenase, phosphoglucoisomerase phosphoglucomutase) were analyzed in sixteen natural population (fi…
Hereditary breast and ovarian cancer in families from southern Italy (Sicily)—Prevalence and geographic distribution of pathogenic variants in BRCA1/…
2020
Recent advances in the detection of germline pathogenic variants (PVs) in BRCA1/2 genes have allowed a deeper understanding of the BRCA-related cancer risk. Several studies showed a significant heterogeneity in the prevalence of PVs across different populations. Because little is known about this in the Sicilian population, our study was aimed at investigating the prevalence and geographic distribution of inherited BRCA1/2 PVs in families from this specific geographical area of Southern Italy. We retrospectively collected and analyzed all clinical information of 1346 hereditary breast and/or ovarian cancer patients genetically tested for germline BRCA1/2 PVs at University Hospital Policlini…
HLA Class I and Class II Polymorphism in Three Sicilian Populations
2007
Two human leukocyte antigen (HLA) class I loci (HLA-A and HLA-B) and one class II locus (HLA-DR) were typed at the DNA level in the Sicilian population. Study participants were of Sicilian origin (183 for class I loci and 260 for class II loci) and live in three towns, chosen on the basis of geographic position and different historical events. These towns are Sciacca (southwest Sicily, located at sea level, conquered by Arabs in a.d. 814), Piana degli Albanesi (northwest Sicily, 720 m above sea level, has maintained religious, cultural, and linguistic peculiarities traced to Albanian settlement in 1488), and Troina (northeast Sicily, 1,120 m above sea level, known as the first settlement of…
COMPOSITION OF THE ESSENTIAL OILS IN CALENDULA SUFFRUTICOSA (ASTERACEAE) FROM SICILY
2016
The genus Calendula L. (Calenduleae Cass., Asteraceae) includes several species having medicinal properties. Pharmacological studies reveal, for instance, that C. officinalis L. exhibits antibacterial, antiviral, antinflammatory, antitumor and antioxidant properties; C. arvensis L. has antibacterial, antinflammatory, antimutagenic and haemolytic activities; C. suffruticosa Vahl has antimicrobial activity, especially against pathogenic microorganisms as Pseudomonas syringae Van Hall, Pseudomonas fluorescens (Flügge) Migula, Xanthomonas campestris (Pammel) Dowson and Agrobacterium tumefaciens Smith & Townsend. Nevertheless, despite a long tradition of use of the above species, and others,…
Taxonomic remarks and distribution of Smyrnium dimartinoi (Apiaceae)
2016
Smyrnium L., an Eurasian genus of the family Apiaceae, includes about 20 taxa of which only 7 are accepted at specific rank; among these, 5 are native to Europe (Tutin & al. 1968; Gomez 2003). In the Italian flora, the genus is represented by 3 taxa also occurring in Sicily (Pignatti 1982; Giardina & al. 2007); these are Smyrnium olusatrum L., S. perfoliatum L. and S. rotundifolium Mill. The last one has also been treated at the rank of subspecies under S. perfoliatum [S. perfoliatum subsp. rotundifolium (Mill.) Hartvig] (Strid 1986; Conti & al. 2005), or as a variety [S. perfoliatum var. rotundifolium (Mill.)Fiori (Fiori 1925)]. In Sicily, same populations related to S. perfoli…
Valorizzazione produttiva della biodiversità in ambiente mediterraneo: il genere Hypericum
2014
Una conoscenza approfondita delle specie appartenenti al genere Hypericum, finalizzata alla loro introduzione negli ordinamenti colturali come specie di interesse industriale e/o ornamentale, comporta la dettagliata descrizione dei parametri morfologici e ambientali delle piante nei loro siti di vegetazione spontanea, e l’accertamento delle loro caratteristiche fitochimiche. Negli anni 2012-2013 è stata svolta un’attività di ricognizione a tale scopo. In Sicilia le perlustrazioni svolte hanno portato all'individuazione di 23 accessioni di H. perforatum, H. perfoliatum, H. pubescens, H. tetrapterum e H. calycinum; numerose altre se ne sono aggiunte, provenienti dall’appennino tosco-romagnolo…
Distribution of KIR Genes and Their HLA Ligands in Different Viral Infectious Diseases: Frequency Study in Sicilian Population
2022
Natural killer (NK) cells play a role in defence against viral infections by killing infected cells or by producing cytokines and interacting with adaptive immune cells. Killer immunoglobulin-like receptors (KIRs) regulate the activation of NK cells through their interaction with human leucocyte antigens (HLA). Ninety-six Sicilian patients positive to Human Immunodeficiency Virus-1 (HIV) and ninety-two Sicilian patients positive to SARS-CoV-2 were genotyped for KIRs and their HLA ligands. We also included fifty-six Sicilian patients with chronic hepatitis B (CHB) already recruited in our previous study. The aim of this study was to compare the distribution of KIR–HLA genes/groups of these t…